CBI Home Research Team Partners Contact 

The ARC Training Centre in Biopharmaceutical Innovation aims to transform Australia’s growing biopharmaceutical industry, an advanced manufacturing capability contributing to Australia’s economic growth.

The ARC Training Centre for Biopharmaceutical Innovation is multi-million dollar Australian Government initiative under the Australian Research Council Industrial Transformation Research Programme.

The CBI combines the research and development, and manufacturing expertise and capabilities of the industry partners and The University of Queensland (UQ). Industry-driven research projects ensures industry-ready graduates drive growth in the sector.  The CBI housed within the Australian institute for Bioengineering and Nanotechnology (AIBN) at UQ and collaborates with the National Biologics Facility, also housed within the AIBN. The Centre combines the research and development, and manufacturing expertise and capabilities of the industry partners and the University of Queensland. Industry-driven research projects ensures industry-ready graduates drive growth in the sector.

The Centre will conduct research projects within three thematic areas:

  • Discovery of new biopharmaceuticals and diagnostic agents
  • Development of mammalian cells as factories for recombinant protein production
  • Manufacturing of biopharmaceuticals

 

The training and research outcomes of the CBI will lead to new biopharmaceuticals and antibody-based reagents, enhanced production methods, improved manufacturing capabilities and a cohort of specialist scientists, which will benefit the economy and positively impact health-care.

The CBI partners with leading Australian stakeholders in the biologics industry   including CSL Limited, GE Healthcare, the Australian Red Cross Blood Service and Patheon Biologics Australia Pty Ltd. The CBI aims to blend research excellence with industry partner experience and know-how.

  • CBI Research

    CBI Home Research Team Partners Contact

    CBI will conduct research projects within three thematic areas

    Discovery of new biopharmaceuticals and diagnostic agents

    The research plan for thematic research area 1 is directed towards the discovery of new biopharmaceuticals and mAbbased reagents utilising innovative methodologies in therapeutic and diagnostic mAb discovery, as well as the development of platform technologies for mAb delivery to intracellular targets. The plan incorporates five distinct projects that will run in parallel, with one student per project.

    Development of mammalian cells as factories for protein manufacturing

    The paradigm shift for researchers from protein expression to protein manufacturing is often an early roadblock when researchers embark on the translation of research. The objective of thematic research area 2 will be to understand cellular bottlenecks for production of therapeutic proteins and bypass those bottlenecks by identifying and modifying relevant cellular pathways, engineering the therapeutic proteins for improved expression and/or manipulating the manufacturing process.7, 8 The plan for thematic research area 2 incorporates two separate projects that will be undertaken in parallel, with one student per project.

    Manufacturing of biopharmaceuticals

    Large-scale cell culture and downstream processing represent the greatest driver of cost of goods (COGs) for biopharmaceuticals. Process improvements to provide gains in product quality, yield and characterisation are the objective for thematic research area 3. The plan includes seven separate projects, each to be conducted in parallel with one student per project.

    #content-image-table {display:none;} .button1 { border: 1px solid #3994c9 !important; padding: 10px; color: #186a9a !important; text-decoration: none; margin: 5px; display:inline-block; } .button...
  • CBI Team

    CBI Home Research Team Partners Contact

    CBI Team

     

    • Director
      Centre for Biopharmaceutical innovation

      Senior Group Leader
      Australian Institute for Bioengineering and Nanotechnology 

      • Deputy Director
        Centre for Biopharmaceutical innovation

        Research Fellow
        Australian Institute for Bioengineering and Nanotechnology
         
      • Centre Manager
        Centre for Biopharmaceutical innovation
         
      • Professorial Research Fellow
        Institute for Molecular Bioscience 
        Affiliate Professor & Group Leader
        Australian Institute for Bioengineering and Nanotechnology
         
      • Professor
        School of Chemistry and Molecular Biosciences
        Faculty of Science
        Affiliated Professor
        Centre for Plant Science
        Queensland Alliance for Agriculture and Food Innovation
      • Principal Research Fellow
        Institute for Molecular Bioscience
         
      • Professorial Research Fellow
        Australian Institute for Bioengineering and Nanotechnology
         
      • Research Fellow in Metabolomics
        Australian Institute for Bioengineering and Nanotechnology 
        Affiliate Research Fellow
        The University of Queensland Diamantina Institute
        Faculty of Medicine
        Affiliate Research Fellow
        School of Pharmacy
        Faculty of Health and Behavioural Sciences
      • Research Fellow
        Centre for Advanced Imaging 
        Affiliate Research Fellow
        Australian Institute for Bioengineering and Nanotechnology
         
      • Director, PEF
        Australian Institute for Bioengineering and Nanotechnology
         
      • Director of Flow Cytometry
        Queensland Brain Institute 
        Director of Flow Cytometry
        Australian Institute for Bioengineering and Nanotechnology
         
      • NHMRC Career Development Fellow
        School of Chemistry and Molecular Biosciences
        Faculty of Science
      • Head of School
        School of Chemistry and Molecular Biosciences
        Faculty of Science
        Affiliate Professor
        Australian Institute for Bioengineering and Nanotechnology 
        Affiliated Professor
        Institute for Molecular Bioscience 
      • Senior Group Leader
        Australian Institute for Bioengineering and Nanotechnology
      • Associate Group Leader
        Australian Institute for Bioengineering and Nanotechnology
      • Lecturer
        School of Chemical Engineering
        Research Fellow
        Australian Institute for Bioengineering and Nanotechnology
    •  

     

    .button1 { border: 1px solid #3994c9 !important; padding: 10px; color: #3994c9 !important; text-decoration: none; margin: 5px; display:inline-block; } .button1:hover { background: #3994c9; ...
  • Contact CBI

    CBI Home Research Team Partners Contact

    Contact CBI

    Director

    Professor Stephen Mahler
    T: +61 7 3365 4172
    M: +61 412 012 844
    E: s.mahler@eng.uq.edu.au

    Centre Manager

    Nancy Eluigwe
    T: +61 7 3346 4268
    F: +61 7 3346 63973
    E: n.eluigwe@uq.edu.au

    Mailing/Delivery Address

    Australian Institute for Bioengineering
    and Nanotechnology (AIBN)
    Corner College and Cooper Rds (Bldg 75)
    The University of Queensland
    Brisbane Qld 4072
    Australia

     

     

    #content-image-table {display:none;} .button1 { border: 1px solid #3994c9 !important; padding: 10px; color: #186a9a !important; text-decoration: none; margin: 5px; display:inline-block; } .button...
  • CBI Partners

    CBI Home Research Team Partners Contact

    CBI Partners

     

    CSL Ltd

    CSL is a global specialty biotherapeutics company that aims to help people with life-threatening medical conditions live a full life by developing and delivering innovative life-saving biotherapies.

    With major facilities in Australia, Germany, Switzerland, United Kingdom and the U.S., CSL employs over 17,000 employees working in more than 30 countries.


     

    Patheon Biologics Pty Ltd

    Patheon Biologics is a global company within the life and material sciences industry that delivers innovative products aimed at improving quality of life. The company's Biologics headquarters are in the Netherlands, with locations on five continents.

    Patheon offers services across the value chain, combining the corporate strength of a large multi-national corporation with the focus and flexibility needed in successful partnerships with biopharmaceutical customers.


     

    Australian Red Cross Blood Service

    The Australian Red Cross Blood Service is a division of the Australian Red Cross. The organisation is funded by the federal, state and territory governments of Australia to supply the community with safe, high quality blood and blood products, as well as organ and bone marrow services for transplantation.


     

    GE Healthcare

    GE Healthcare is shaping a new age of patient care by providing transformational medical technologies and services.

    GE’s broad expertise in medical imaging and information technologies, biopharmaceutical manufacturing technologies, drug discovery, patient monitoring systems, medical diagnostics, performance improvement and performance solutions services help their customers to deliver better care that is affordable to more people around the world.

     

     

    #content-image-table {display:none;} .button1 { border: 1px solid #3994c9 !important; padding: 10px; color: #186a9a !important; text-decoration: none; margin: 5px; display:inline-block; } .button...
Go to top