Professor Justin Cooper-White, above, and his research on meniscus regeneration explained, below.
Professor Justin Cooper-White, above, and his research on meniscus regeneration explained, below.
BE (Chem) (Hons) UQ, PhD UQ
Group Leader

Contact

Telephone: +61 7 334 63858 Email: j.cooperwhite@uq.edu.au

Research: Elucidating the microenvironmental cues that regulate stem cell behaviours and translating those insights into biomaterial scaffolds and microdevices to direct stem cell differentiation

Professor Justin Cooper-White is a global leader in using engineering to solve problems in biology. In addition to holding the position of AIBN Group Leader, Professor Cooper-White is Director of the Australian National Fabrication Facility-Queensland Node and is one of only 13 CSIRO Office of the Chief Executive Science Leaders across the country. He is a past President of both the Australasian Society for Biomaterials and Tissue Engineering and the Australian Society of Rheology and has previously served as an Associate Dean (Research) at the UQ Faculty of Engineering, Architecture and Information Technology.

International links

Professor Cooper-White has many past and currently active international collaborations with world leading research groups at MIT (US); Stanford (USA); ETH (Switzerland); EPFL (Switzerland); SNU (Korea); University Of Grenoble (France); Politecnico di Milano (Italy); UCL (UK); and the Max Planck Institute (Germany). He has performed contract research and consultancy work for Unilever in the UK; Nestle International, Switzerland; Rhodia, US; Inion, Finland since 2001 and a Queensland primary business. He has previously held a Visiting Professor Fellowship (2007) at ETH Zurich and a Politecnico di Milano Visiting Professor Fellowship (2012-2013). He is the associate editor of the Korean-Australian Rheology Journal; serves or has served on the editorial boards of Biomaterials Science, Rheological Acta, Soft Materials, Biomicrofluidics and the Open Biomedical Engineering Journal; and is a reviewer of major international journals, including Nature Methods, Advanced Materials, Lab on a Chip, Stem Cells, Stem Cells and Development, Biomacromolecules, Tissue Engineering, Langmuir, Biomaterials and Journal of Non-Newtonian Fluid Mechanics.

Memberships, patents and funding

Professor Cooper-White has been chair or co-chair of three international conferences, focusing on either rheology or biomaterials and tissue engineering: the Australian representative on the International Advisory Committee, 15th International Congress on Rheology, Monterey, US; a member of the International Scientific Advisory Committee for the World Congress on Biomaterials, Amsterdam, Netherlands; and currently an Australian representative on the Interntional Union of Societies for Biomaterials Science and Engineering (IUSBE). He is the inventor on six international patents. He has performed contract and sponsored research work for multinationals such as Mesoblast, Rhodia, Unilever and Nestle International and has received more than $45 million in competitive grant funding.

Awards and plenaries

Recognition of Professor Cooper-White’s standing in the research field is reflected in the nine plenary and more than 25 keynote presentations he has been invited to give at national and international conferences since 2001. He received the 2005 Annual Award of the British Society of Rheology for contributions to the fields of rheology and non-Newtonian fluid mechanics. His work on engineered surfaces, specifically for directing mesenchymal stem cell fate was highlighted as one the most influential works on stem cell – biomaterial interactions at the 2008 World Biomaterials Congress in Amsterdam, the Netherlands.

Key publications in the past five years

The effect of time-dependent deformation of viscoelastic hydrogels on myogenic induction and Rac1 activity in mesenchymal stem cells
Cameron, Andrew R., Frith, Jessica E., Gomez, Guillermo A., Yap, Alpha S and Cooper-White, Justin J. (2014) The effect of time-dependent deformation of viscoelastic hydrogels on myogenic induction and Rac1 activity in mesenchymal stem cells. Biomaterials, 35 6: 1857-1868.

Modulation of stem cell adhesion and morphology via facile control over surface presentation of cell adhesion molecules
Li, Haiqing, Frith, Jessica and Cooper-White, Justin J. (2014) Modulation of stem cell adhesion and morphology via facile control over surface presentation of cell adhesion molecules. Biomacromolecules, 15 1: 43-52.

Effects of bound versus soluble pentosan polysulphate in PEG/HA-based hydrogels tailored for intervertebral disc regeneration
Frith, Jessica E., Menzies, Donna J., Cameron,Andrew R., Ghosh, P., Whitehead, Darryl L., Gronthos, S., Zannettino, Andrew C.W. and Cooper-White, Justin J. (2014) Effects of bound versus soluble pentosan polysulphate in PEG/HA-based hydrogels tailored for intervertebral disc regeneration. Biomaterials, 35 4: 1150-1162.

Effects of cell density and biomacromolecule addition on the flow behavior of concentrated mesenchymal cell suspensions
Maisonneuve, Benoît G. C., Roux, Denis C. D., Thorn, Peter and Cooper-White, Justin J. (2013) Effects of cell density and biomacromolecule addition on the flow behavior of concentrated mesenchymal cell suspensions. Biomacromolecules, 14 12: 4388-4397.

Microbioreactor array screening of Wnt modulators and microenvironmental factors in osteogenic differentiation of Mesenchymal progenitor cells
Frith, Jessica E., Titmarsh, Drew M., Padmanabhan, Harish and Cooper-White, Justin J. (2013) Microbioreactor array screening of Wnt modulators and microenvironmental factors in osteogenic differentiation of Mesenchymal progenitor cells. PLoS One, 8 12: e82931.1-e82931.15.

Gelation Kinetics and Viscoelastic Properties of Pluronic and alpha-Cyclodextrin-Based Pseudopolyrotaxane Hydrogels
Pradal, Clementine, Jack, Kevin S., Grondahl, Lisbeth and Cooper-White, Justin J. (2013) Gelation Kinetics and Viscoelastic Properties of Pluronic and alpha-Cyclodextrin-Based Pseudopolyrotaxane Hydrogels. Biomacromolecules, 14 10: 3780-3792.

Full factorial screening of human embryonic stem cell maintenance with multiplexed microbioreactor arrays
Titmarsh, Drew M., Ovchinnikov, Dmitry A., Wolvetang, Ernst J. and Cooper-White, Justin J. (2013) Full factorial screening of human embryonic stem cell maintenance with multiplexed microbioreactor arrays. Biotechnology Journal, 8 7: 822-834.

Tailorable cell culture platforms from enzymatically cross-linked multifunctional poly(ethylene glycol)-based hydrogels
Menzies, Donna J., Cameron, Andrew, Munro, Trent, Wolvetang, Ernst, Grondahl, Lisbeth and Cooper-White, Justin J. (2013) Tailorable cell culture platforms from enzymatically cross-linked multifunctional poly(ethylene glycol)-based hydrogels. Biomacromolecules, 14 2: 413-423.

Lateral spacing of adhesion peptides influences human mesenchymal stem cell behaviour
Frith, Jessica E., Mills, Richard J. and Cooper-White, Justin J. (2012) Lateral spacing of adhesion peptides influences human mesenchymal stem cell behaviour. Journal of Cell Science, 125 2: 317-327.

Cameron AR, Frith JE, Cooper-White JJ. (2011) The influence of substrate creep on mesenchymal stem cell behaviour and phenotype. Biomaterials 32(26), 5979-5993.

Hudson JE, Brooke G, Blair C, Wolvetang EJ, Cooper-White JJ. (2011) Development of myocardial constructs using modulus-matched acrylated polypropylene glycol triol substrate and different nonmyocyte cell populations. Tissue Engineering - Part A 17(17-18), 2279-2289.

Vaquette C, Cooper-White JJ. (2011) Increasing electrospun scaffold pore size with tailored collectors for improved cell penetration. Acta Biomaterialia 7(6) 2544-57.

Tan GK, Dinnes DLM, Butler LN, Cooper-White JJ. (2010) Interactions between meniscal cells and a self-assembled biomimetic surface composed of hyaluronic acid, chitosan and meniscal extracellular matrix molecules. Biomaterials 31(23), 6104-6118.

Chau L, Doran M, Cooper-White JJ. (2009) A novel multishear microdevice for studying cell mechanics. Lab Chip 9(13), 1897-1902.

George PA, Donose BC, Cooper-White JJ. (2009) Self-assembling polystyrene-block-poly(ethylene oxide) copolymer surface coatings: Resistance to protein and cell adhesion. Biomaterials 30(13) 2449-2456.

Rowlands AS, George PA, Cooper-White JJ. (2008) Directing osteogenic and myogenic differentiation of MSCs: interplay of stiffness and adhesive ligand presentation. American Journal of Physiology Cell Physiology 295(4), C1037-1044.

Professor Justin Cooper-White section

The Cooper-White Lab Group: TE&M

Meet the Cooper-White Lab Group

TE&M Research Areas

TE&M lab works at the interface of stem cell biology, materials science, engineering and microfluidics

Current 2015 TE&M Research Projects

We are seeking highly motivated young researchers with a 1st Class Honours to join our innovative and exciting team

TE&M 2015 Post-Graduate Research Projects

We are seeking highly motivated young researchers with a 1st Class Honours to join our innovative and exciting team
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