Trau research projects
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	New biomarker centre to develop early disease diagnosis
	PhD Scholarships

Professor Trau’s group focuses on the formation of novel materials and devices for medical and diagnostic needs. Examples of these include devices for rapid DNA sequencing, genetic screening, diagnostics, drug and biomarker discovery. Other devices of interest are artificial tissue matrices for human bone, liver and pancreas tissue. Nanotechnology, the ability to control and manipulate nanometer-sized features of matter, is a fundamental tool which is used to fashion such materials & devices.

Research Projects

• Nanoscaled Platforms for Biosensing
• Multiplexed Molecular Reading of Protein Associations via Nanoscaled Devices
• Biocompatible Nanocomposites for Tissue Regeneration
• Biomarker Discovery, Detection and Use
• Nanoscaled Systems for Biosecurity

 

Key Publications (Top 10 Last 5 years) 

1. Vogel, Robert; Surawski, Peter P. T.; Littleton, Bradley N.; Miller, Chris R.; Lawrie, Gwendolyn A.; Battersby, Bronwyn J.; Trau, Matt. Fluorescent organosilica micro- and nanoparticles with controllable size. Journal of Colloid and Interface Science (2007), 310(1), 144-150.
2. S.M. Cool, B. Kenny, A. Wu, V. Nurcombe, M. Trau, A. I. Cassady, and L. Grøndahl “Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Composite Biomaterials for Bone Tissue Regeneration: In vitro Performance Assessed by Osteoblast Proliferation, Osteoclast Adhesion and Resorption, and Macrophage Pro-inflammatory Response” Journal of Biomedical Materials Research Part A, Feb 21, 2007.
3. Angus P.R. Johnston, Bronwyn J. Battersby, Gwendolyn A. Lawrie, Lynette K. Lambert, and Matt Trau, A Mechanism for Forming Large Fluorescent Organo-Silica Particles: Potential Supports for Combinatorial Synthesis, Chemistry of Materials 18 (26): 6163-6169 DEC 26 2006
4. Lawrie, G., Grøndahl, L., Battersby, B., Keen, I., Lorentzen, M., Surawski, P., and Trau, M., (2006) “Tailoring surface properties to build colloidal diagnostic devices: controlling interparticle associations” Langmuir 22(1), 497-505.
5. Johnston, A.P.R., Battersby, B.J., Lawrie, G.A., Trau, M. (2005) "Porous functionalised silica particles: a potential platform for biomolecular screening" Chem. Commun., 848-850.
6. Miller, C.R., Vogel, R., Surawski, P.P.T., Jack, K.S., Corrie, S.R. and Trau, M. (2005) “Functionalized Organosilica Microspheres via a Novel Emulsion Route ” Langmuir 21(21), pp 9733-9740.
7. Lawrie, Gwendolyn A.; Battersby, Bronwyn J.; Trau, M. (2003) “Synthesis of optically complex core-shell colloidal suspensions: Pathways to multiplexed biological screening”. Advanced Functional Materials 13(11), 887-896.
8. Brodsky, A.S., Johnston, A.P.R., Trau, M., Silver, P.A., (2003) “Analysis of RNA-protein interactions by flow cytometry”, Current Opinion in Molecular Therapeutics, 5(3):235-240.
9. Battersby, B.J., Lawrie, G.A., Johnston, A.P.R., Trau, M. (2002) “Optical Barcoding of Colloidal Suspensions: Applications in Genomics, Proteomics and Drug Discovery” Chem. Comm. 14, 1435-1441.
10. Battersby, B.J., Trau, M. (2002) “Novel Miniaturized Systems in High Throughput Screening” Trends in Biotechnology 20, 167-173.