Medical diagnostic testing based on needle-free devices applied to the skin
Nanobiotechnology, Health, Materials, Diagnostics, Biomaterials, Infectious Disease, Surface chemistry, Protein Expression, Pre-clinical testing, Biomedical engineering, Skin physiology, Biomarker detection, Resource-limited settings
Sampling and processing of blood for diagnostic tests is a key limitation to disease diagnosis and routine monitoring. Currently available tests usually require lab infrastructure, painful procedures for patients, long waits for results and added costs on strained healthcare budgets. In this project we are developing “Micropatches” – silicon or polymer chips that contain thousands of tiny micro-projections that can breach the skin and selectively capture disease-related proteins and antibodies from the underlying blood vessels and tissue fluid. We are designing these devices to be pain-free, to detect multiple protein/antibody biomarkers in the one test, and to be used in a GP, outpatient clinic, or home setting.
There are many aspects to this project, requiring a number of skill sets, ranging from microfabrication, surface modification and protein chemistry through to skin biology, immunology and pre-clinical device testing in animal models. We currently have projects available for undergraduate, Honours, MPhil and PhD students from diverse backgrounds (engineering, chemistry, biochemistry, microbiology) to tackle different aspects of the project.
|Lead investigator||Dr Simon Corrie
|Research group||Kendall Group|