SERS platform for rapid and multiplexed point-of-care diagnosis by pull-down strategy in muniaturization flow-through system.
SERS platform for rapid and multiplexed point-of-care diagnosis by pull-down strategy in muniaturization flow-through system.

Project keywords

surface-enhanced Raman spectroscopy, biomarker, multiplex, Plasmonic nanoassemblies, rapid, point-of-care diagnosis

Project summary

The central aim of this project is to develop a novel technology/sensor platform for rapid and ultrasensitive detection of multiple biomarkers for breast cancer from simulated body fluids and in clinic by magnetic pulling-down immunoassay using rational designed, tailor-made surface-enhanced Raman spectroscopy (SERS) active super plamsonic nanostructures in a miniaturised flow-through system. 3D plasmonic superstructures as novel SERS labels will be rationally designed and characterised at single-particle level. Tumor biomarkers for breast cancer will be employed as the model target for establishing the detection platform in a portable configuration for point-of-care diagnostics.

Project contacts

Lead investigator Dr Yuling Wang; Prof Matt Trau
Research group Trau Group
Contact email m.trau@uq.edu.au, y.wang27@uq.edu.au

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