• About Systems & Synthetic Biology

    The human genome project inspired the development of high throughput, low cost omics technologies. We can now sequence a microbe in a morning and do a comprehensive molecular inventory (expressed genes, proteins, metabolites) in a week. Thousands of healthy and aberrant human tissue samples are being sequenced to determine diversity of normal and aberrant human genomes and their expression. Further, we are rapidly moving towards producing complete molecular inventories for each individual cell in an organism.

    Enumerating the components in a biological system does not yield understanding in itself. Systems biology uses systems sciences, modeling and simulation to integrate the data streams and convert them into knowledge. As applied systems biologist or systems biotechnologists, however, we do more than developing tools for better understanding (analysis); we use these tools to design products and processes for human benefit (synthesis). We are rapidly moving from retrofitting living systems with a single or few genes using genetic engineering, to the design of living systems from scratch using systems and synthetic biology.

    Approach

    Our approach is captured in the classical 4M framework (manipulate, measure, mine and model) with its two dimensions: dry versus wet biology and synthesis versus analysis. At AIBN Systems & Synthetic Biology, we work both on developing the fundamentals of this emerging science and its application to a broad range of living systems. Moreover, we work closely with colleagues in other disciplines and a number of companies interested in pursuing emerging opportunities in this field.

    The human genome project inspired the development of high throughput, low cost omics technologies. We can now sequence a microbe in a morning and do a comprehensive molecular inventory (expressed genes, proteins, metabolites) in a week. Thousa...
  • Projects
  • Resources

    We run the Queenlsand Node of Metabolomics Australia. The facility is available to the public. For further details.

    We run the Queenlsand Node of Metabolomics Australia. The facility is available to the public. For further details.
  • People
  • Join CSSB

    Postdoctoral Research Fellowships

    All research positions are advertised on UQ Jobs (see current list below). A number of competitive research fellowships area available locally (e.g., UQ Postdoctoral Research Fellowship, Queensland Government Accelerate Scheme), nationationally (e.g., DECRA, Future Fellowships), and interenationally (e.g., Marie Curie, Becas Chile). We have a good track record of helping competitive candidates win fellowships. Please contact us early for an assessment of potential and help with formulating a compelling proposal aligned with our research strengths.

    Research Higher Degree Opportunities

    We always have openings for high quality research students. UQ accepts research students any time of the year through a streamlined process with one application form.

    Most students will study on general scholarships and projects will be developed in collaboration between the student and supervisor. Please review our projects and contact the listed researcher to discuss possibilities. If you come to an agreement with a supervisior, you can start the formal process of applying for admission and scholarship explained in the student section. Scholarships for particular projects are occasionally advertised (see current list below).

    Occupational Traineeships

    We encourage applications from qualified Occupational Trainees who are interested in short research projects related to our areas of interest.

    • Domestic (Australian/New Zealand) applicants should identify a broad area of interest focused around one of our research projects and email a brief CV to the appropriate Lead Investigator.
    • International applicants: Information about the occupational traineeship visa supported by the Australian Government Department of Immigration and Citizenship can be found here (http://www.immi.gov.au/Visas/Pages/402.aspx). Please read this information carefully to determine whether or not you are eligible. If you are eligible, you should then identify a broad area of interest focused around one of our research projects and email a brief CV to the appropriate Lead Investigator. Please note that due to the cost and time effort involved, we generally do not accept international occupational trainees for less than 3 months.


    Your CV will be assessed for suitability and you will be contacted with further information.

    Current vacancies
  • Contact CSSB

    Systems and Synthetic Biology
    Level 3, Australian Institute for Bioengineering & Nanotechnology (AIBN)
    Cnr College and Cooper Roads
    The University of Queensland
    Brisbane, QLD 4072, Australia

    Professor Lars Keld Nielsen
    t: (+61) 7 3346 3986
    f: (+61) 7 3346 3973
    e: lars.nielsen@uq.edu.au
     

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    Systems and Synthetic Biology Level 3, Australian Institute for Bioengineering & Nanotechnology (AIBN) Cnr College and Cooper Roads The University of Queensland Brisbane, QLD 4072, Australia Professor Lars Kel...
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