AIBN has a dynamic research environment with teams working at the interface of the biological, chemical and physical sciences. The Institute conducts world-class research in nanoscale science, technology and engineering and is committed translating this research into commercial outcomes.
Integral to AIBN's ongoing research success is a unique combination of facilities and capabilities.
The $75 million AIBN is a triumph in research institute architecture.
As part of the joint UQ, Queensland Government and The Atlantic Philanthropies-funded project, Jackson/S2F Architectural Joint Venture has created a six-level facility which blends effortlessly into its eucalypt and rainforest surrounds and is safeguarded from the energy-sapping effects of the sun.
After just over two years of construction, the building features a gross floor area of 15,689 square metres.
The architects have created a building that brings together key University research groups from the biological, chemical and physical sciences.
In fact, the AIBN, connected to the neighbouring Molecular Biosciences Building by a walkway, will house up to 365 staff and research students, including many returning to Australia from overseas, as well as those attracted from local and interstate institutions.
To combat the effects of Brisbane’s subtropical climate, sun-shading devices consisting of metallic fins have been installed on windows on the southern side, with devices consisting of a finer filagree screen of perforated metal slats on the northern and eastern sides.
The complex will consist mainly of research laboratories – 16 in total – with the three largest measuring 278, 281 and 303 square metres in area.
Specialist facilities in the AIBN include:
- Cell and tissue culture facilities;
- Nanoparticle production and analysis capabilities;
- Polymer Synthesis and Characterisation;
- Microanalysis; and
- Ultra-High Performance Flow Cytometry.
The building also features:
- Reticulation systems for essential scientific gases such as natural gas, nitrogen and carbon dioxide, as well as vacuum and compressed air to outlets throughout the facility
- 58 fume cupboards ensuring a safe working environment
- A back-up electrical generator designed to maintain AIBN’s critical samples during power outages
- A human-made, rock-lined water course and
- Bicycle racks and associated changing facilities.
AIBN has a dynamic research environment with teams working at the interface of the biological, chemical and physical sciences. The institute conducts world-class research in nanoscale science, technology and engineering and is committed translating this research into commercial outcomes.
Integral to AIBN's ongoing research success is a unique combination of facilities and capabilities, which includes the National Research and Development Infrastructure.
The infrastructure is valued at over $30 million and was established with the strong support of the National Collaborative Research Infrastructure Strategy (NCRIS), the Queensland government and The University of Queensland. The expertise and equipment available enables AIBN and the Australian research community to conduct globally competitive research in:
Embedded in the AIBN's integrated multidisciplinary research environment, the infrastructure maximises the value of the institute's strong industry focus by:
- Promoting linkages with local companies;
- Assisting in the development of new industries; and
- Advancing the AIBN's translational research programs.
The infrastructure ensures that AIBN plays a leading role in increasing the number of Queensland and Australian businesses undertaking research, development and innovation.
The Infrastructure's expertise and equipment are available to the broader Australian research community, which includes industry, academia and private organisations.AIBN has a dynamic research environment with teams working at the interface of the biological, chemical and physical sciences. The institute conducts world-class research in nanoscale science, technology and engineering and is committed translating ...
The AIBN Centre for Theoretical and Computational Molecular Science (CTCMS) brings together leading researchers developing and using theories and computational techniques for molecular science from across The University of Queensland (UQ).
The CTCMS has a computational facility installed in the Australian Institute for Bioengineering and Nanotechnology (AIBN) at the University of Queensland. It consists of 260 DELL CPU cores with approximately 6GB RAM per core, 240 Intel Xeon Phi co-processor cores, an InfiniBand network and 130 TB disk space.
The four main research themes of the Centre are:
- Theory and Algorithm Development
- Theory and Computation: Materials
- Theory and Computation: Fluids
- Theory and Computation: Biomolecular Systems
The capabilities of the Queensland Node of the Australian National Fabrication Facility (ANFF-Q) are available to all of the Australian research and development community, including industry and private research organisations. The Node has equipment and expertise in patterning of polymer and glass substrates, the production of novel substrates for immunotherapy and drug delivery, the fabrication of microfluidic devices and a globally unique SiC on Si Epitaxial reactor.
Research and industry groups have the option of working in ANFF-Q’s laboratories with access to experts in nanofabrication and characterisation or having their devices fabricated according to specification. The facility can also perform characterization work on external samples.
The $12 million ANFF-Q consists of two facilities: the Soft Materials Processing Facility; and the BioNano Device Fabrication Facility, located at The University of Queensland; and the Queensland Microtechnology Facility; and the Raman Spectroscopy Facility, housed at Griffith University. The facilities are embedded in innovative and integrated institutes and centres that provide a dynamic, exciting and collaborative atmosphere where researchers can get the most from their ideas with the best possible support and world class equipment. These centres are namely the Australian Institute for Bioengineering and Nanotechnology, the Centre for Organic Photonics and Electronics and the Queensland Micro and Nanotechnology Centre.
Both facilities are located at the University of Queensland, with the Bio-Nano-Device Fabrication Facility located in the Australian Institute for Bioengineering and Nanotechnology and the Soft Materials Processing Facility in the School of Chemistry and Molecular Biosciences’ Centre for Organic Photonics and Electronics.
ANFF-Q’s capabilities combine state-of-the-art equipment not found elsewhere in Australia and appropriately housed in class 1000 and 10,000 clean rooms, with the expertise of highly experienced research staff. The Node’s expertise includes:
- The ability to undertake patterning of surfaces and devices with nanometer precision;
- The design, manufacture, profiling and surface characterisation of microfluidic devices;
- Analytical support for research in the areas of nanostructures, polymeric materials and electrostatics;
- Production of high resolution images and precise examination of complex biological systems;
- The ability to synthesise and characterise functional nanoparticles and bio-inspired nanomaterials;
- The manufacture, analysis and characterisation of innovative functional materials for photolithography, tissue engineering and targeted drug delivery systems and new material development;
- Functional organic (photonics and electronics) synthesis, device testing and characterisation services;
- Precise printing of micro-scale structures on organic and inorganic nanoparticle materials;
- Characterisation and testing of solar cells; and
- Silicon based multi-layer substrates for microelectronics.
- The Centre for Microscopy and Microanalysis (CMM) is an interdisciplinary research, teaching and service centre which also plays an integral role within the science programs of The University of Queensland.
Through the AIBN/QBI joint appointment of Dr Geoff Osborne, AIBN researchers have access to an extensive suite of flow cytometry instrumentation.
Instruments and expertise include:
For bookings go to http://web.qbi.uq.edu.au/qbi_bookings/day.php?Through the AIBN/QBI joint appointment of Dr Geoff Osborne, AIBN researchers have access to an extensive suite of flow cytometry instrumentation. Instruments and ...
- Cytopeia Influx Cell Sorter: the most advanced cell sorting flow cytometer in the suite of instruments, currently configured with four lasers and nineteen detectors all housed in a Class II certified laminar flow cabinet. This instrument has multi-well plate handling capability for both sample acquisition and deposition making it ideally suited to screening applications of novel compounds on neural cells and selection of subsequent responding cells.
- BD FACSAria Cell Sorter: This high capacity cell sorter fitted with fourteen fluorescent detectors, multi-well plate cell deposition option and aerosol management is ideally placed to fulfill the research needs of scientists requiring more routine multi parametric cell sorting.
- BD FACSVantage SE DiVa Cell Sorter: comprises a three-laser, eight fluorescence detector system capable of sorting for routine applications such as surface markers and DNA binding dyes but also novel particle separations but utilizing nozzles with diameters up to 400um. These large nozzles facilitate the sorting of various neural cell populations that are in some cases, twice as large as those blood cell types that are typically sorted.
- BD LSR II analyzing flow cytometer that can simultaneously detect as many as 18 fluorochromes, which are excited from four individual lasers (UV, 407, 488, 633nm). This instrument increases QBI's analytical capabilities by providing additional excitation wavelengths and making available some of the sorter time that is currently dedicated to analysis.
AIBN hosts the Queensland Node of Metabolomics Australia, part of Bioplatforms Australia. Integrated within the Systems and Synthetic Biology Group, the Queensland node provides specialised expertise in metabolic engineering directed to understanding and manipulating cellular behaviour at a system level.
In addition to conventional metabolomics, AIBN’s facilities are especially set up for metabolic flux analysis, flux balancing and isotopomer modelling. It serves the Australian biotechnology community with the development of fluxomics models that can be used to analyse and engineer mammalian, plant or microbial fermentation systems and employed to optimise product development.
AIBN offers the following services:
- GC-MS and QTOF based untargeted analysis
- Access to Genome scale modelling (experimental & theoretical)
- Metabolic flux analysis from exometabolome
- 13C metabolic flux analysis
- Central carbon metabolism
- Spatiotemporal metabolic flux analysis in multicellular organisms
Current analytical instruments include
- Agilent QTOF 6550 with Agilent UHPLC
- AB Sciex QTRAP 4000 LC/MS/MS system with Dionex HPLC and Agilent CE front-ends
- Agilent GC/MS (2) with Gerstel MultiPurpose Sampler
- Agilent HPLC (3) with DAD, ELSD, RI, and Fluorescence detectors
- Dionex HPAE-PAD system for sugar analysis
Please contact firstname.lastname@example.org for further details and quotes.AIBN hosts the Queensland Node of Metabolomics Australia, part of Bioplatforms Australia. Integrated within the Systems and Synthetic Biology Group, the Queensland node provides specialised expertise in metabolic engineering directed to understandi...
- Focused on emerging nanomaterials research, including the synthesis and characterisation of nanomaterials
The focus of the National Biologics Facility (NBF) is production of high-quality recombinant proteins in pre-clinical or clinical quantities.
The NBF specialises in use of mammalian cell expression technology for proteins with potential therapeutic or commercial uses. The facility was established in 2007 to assist Australian biotechnology companies and academic researchers to bridge the gap between laboratory experiments and the well-characterised cell line and bioprocesses required to produce material at the pilot scale. The NBF has a proven track record in mammalian cell line development and recombinant protein expression and purification at the Queensland node, and various expression systems at the CSIRO's Victoria node.
The Australian Institute for Bioengineering and Nanotechnology (AIBN) at The University of Queensland (UQ) houses the Queensland facility in a specially designed $13 million facility of labs, clean rooms and state-of-the-art equipment. The NBF has a staff of scientists and bioprocess engineers with world-class expertise in molecular biology, antibody engineering, mammalian cell culture, biopharmaceutical development and associated current Good Manufacturing Practices (cGMP).The NBF specialises in:
- Cell line development
- Antibody engineering
- Biologics production
- Protein analytics.
The Protein Expression Facility (PEF) is a UQ central facility offering research groups extensive services in recombinant protein production, purification and training.
PEF has state-of-the-art facilities and a team of highly skilled professionals with vast knowledge in the challenges associated with protein expression and purification.
The PEF team provides infrastructure and training for recombinant protein expression and purification, producing simple protein biomolecules to complex multi-protein biomolecular assemblies, which enables research at UQ and throughout Australia.
PEF specialises in:
Molecular Biology Services
A range of molecular services including construct design, cloning gene of interest into expression vector, site-directed mutagenesis and vector development.
Protein Expression Services
A range of host systems such as bacterial, yeast (Pichia Pastoris or Kluyveromyces lactis), insect cell/baculovirus and transient mammalian cell expression (CHO and HEK293) are available to achieve optimal expression for a variety of uses.
Downstream Processing Services
Protein purification using a range of chromatography techniques (e.g. affinity, size exclusion, ion exchange) and protein analysis (CD, mass spectroscopy).
Training and Consultation Services
Provide training to staff and students interested in protein expression and purification.
The Pluripotent Stem Cell Core Facility is accommodated at AIBN, facilitating pluripotent stem cell research both within the University of Queensland and throughout Australia.Combining extensive expertise and state-of-the-art facilities, the facility offers a range of pluripotent stem cell products, services and training including:
Custom services developed to meet customer requirements.
For more information phone Nilay Thaker on 07 3346 3472 or send an email to email@example.com.The Pluripotent Stem Cell Core Facility is accommodated at AIBN, facilitating pluripotent stem cell research both within the University of Queensland and throughout Australia. Combining extensive expertise and state-of-the-art facilit...